advance diabetes study pdf - The aim of the BP arm asupan gula berlebihan menyebabkan diabetes of the ADVANCE trial was to establish whether routine provision of BPlowering therapy produced additional benefits in terms of macro and microvascular disease irrespective of baseline BP and added to the benefits produced by other cardiovascular preventive therapies including ACE inhibitors The publication of the UK Prospective Diabetes Study UKPDS in 1998 Simon R Heller on behalf of the ADVANCE Collaborative Group A Summary of the ADVANCE Trial 1 November 2009 32 suppl2 S357S361 The publication of the UK Prospective Diabetes Study UKPDS in 1998 helped to shape the management of type 2 diabetes in recent years 1 The study demonstrated several points The ADVANCE study randomized 11140 participants at sites in Europe AustraliaNew Zealand Canada and Asia to a strategy of intensive glycemic control with primary therapy being the sulfonylurea gliclizide and additional medications as needed to achieve a target A1C of 65 or to standard therapy in which any medication but gliclizide Intensive Blood Glucose Control and Vascular Outcomes in Patients with The ADVANCE Trial is the largestever study aimed at investigating the effects of a treatment based on the fixed combination of an ACEinhibitor perindopril 2mg and a diuretic agent indapamide 0625mg on macrovascular and microvascular complications and deaths The main features of ADVANCE can be summarised as follows Intensive Blood Glucose Control and Vascular Outcomes in Patients with The ADVANCE study1 claims that a regimen of perindopril and indapamide reduces vascular morbidity and mortality in patients with type 2 diabetes and one other vascular risk factor Since more than half american diabetes association guidelines 2014 pdf of the patients in the control group were taking perindopril by the end of the study the major difference in treatment was in diuretic use This suggests that the benefit came from the effect What did the ACCORD ADVANCE and VA Diabetes trials show diabetes1214 The Action in Diabetes and Vascular Disease Preterax and Diamicron Modified Release Controlled Evaluation ADVANCE trial was designed to assess the effects on major vascular outcomes PDF A summary of the ADVANCE trial ResearchGate The ADVANCE trial The Lancet PDF A Summary of the ADVANCE Trial Semantic Scholar The ADVANCE Trial results clinical implications and perspectives A Summary of the ADVANCE Trial Diabetes Care Supplementary Appendix nejmadvance2560sa1pdf Download 24053 KB Appendix UK Prospective Diabetes Study UKPDS Group Intensive bloodglucose control with sulphonylureas or insulin By the end of the trial over 90 of patients were still taking a sulfonylurea gliclazide MR in the intensive group compared with 69 in those allocated to standard therapy total of 74 Effects of Intensive Glucose Lowering in Type 2 Diabetes PDF The ADVANCE trial The Lancet The ADVANCE study1 claims that a regimen of perindopril and indapa mide reduces vascular morbidity and mortal ity in patients with type 2 diabetes and one other vascular risk factor Since more than half of the patients in the control group were taking perindopril by the end of the study the major diff erence in treatment was in diuretic use Study rationale and design of ADVANCE action in diabetes and vascular disease preterax and diamicron MR controlled apakah diabetes penyebab impoten evaluation Diabetologia 20014411181120 Crossref
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