advance diabetes study results - What did the ACCORD ADVANCE and VA Diabetes trials show

advance diabetes study results - Effects of blood pressure lowering and rata rata umur penderita diabetes intensive glucose control intervention on renal events in the ADVANCE Study Figure modified from Ref 7 Efficacy and safety of routine blood pressure lowering in older patients with diabetes results from the ADVANCE trial J Hypertens 20102811411149 The ADVANCE trial new findings and updated results Results from randomized controlled trials have demonstrated conclusively that the risk of microvascular complications can be reduced by intensive glycemic control in patients with type 1 12 and type 2 diabetes 35In the Diabetes Control and Complications Trial DCCT there was an 60 reduction in development or progression of diabetic retinopathy nephropathy and neuropathy A Summary of the ADVANCE Trial Diabetes Care Shichiri M Kishikawa H Ohkubo Y Wake N Longterm results of the Kumamoto Study on optimal diabetes control in type 2 diabetes patients Diabetes Care 200023Suppl 2B21B29 PubMed PDF A summary of the ADVANCE trial ResearchGate Intensive Blood Glucose Control and Vascular Outcomes in Type 2 Diabetes n engl j med 35824 wwwnejmorg june 12 2008 2561 T he prevalence of diabetes is increas Rationale and design of the ADVANCE study a randomised trial of blood pressure lowering and intensive glucose control in highrisk individuals with type 2 diabetes mellitus Action in Diabetes and Vascular Disease PreterAx and DiamicroN ModifiedRelease Controlled Evaluation J Hypertens Suppl 200119S2128 13 ACCORD news conference 14 Effects of Intensive Glucose Lowering in Type 2 Diabetes Longterm Benefits of Intensive Glucose Control for Preventing End What did buah naga penderita diabetes the ACCORD ADVANCE and VA Diabetes trials show The publication of the UK Prospective Diabetes Study UKPDS in 1998 helped to shape the management of type 2 diabetes in recent years 1 The study dem has no significant effect in reducing macrovascular disease The results of ADVANCE do not exclude a minor effect on cardiovascular disease indeed cardiovascular mortality was reduced Other epidemiological analyses that were undertaken treated the trial as a cohort study including using biomarkers from the blood samples taken from ADVANCE subjects as risk exposures Results More than 50 publications have reported epidemiological results from ADVANCE The main results from ADVANCEON suggested attenuated benefits of ADVANCE The ADVANCE Trial results clinical implications and perspectives Previous largescale clinical trials such as the UKPDS United Kingdom Prospective Diabetes Study and ADVANCE Action in Diabetes and Vascular Disease Preterax and DiamicronMR controlled UK Prospective Diabetes Study UKPDS Group Mortality results Diabetes 197019Suppl789830 Study rationale and design of ADVANCE action in diabetes and vascular disease preterax Intensive Blood Glucose Control and Vascular Outcomes in Patients with Intensive Blood Glucose Control and Vascular Outcomes in Patients with Posttrial followup of the UK Prospective Diabetes Study UKPDS ADVANCE study that intensive glucose control in patients with type 2 diabetes significantly reduced the risk of a range of renal outcomes including new or worsening The results regarding the effects on ESKD in the longterm followup of the ACCORD trial are awaited Observational analyses bagian nepron terjadinya diabetes from ADVANCE and ADVANCEON

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