ambient air pollution an emerging risk factor for diabetes mellitus - Ambient and TrafficRelated Air Pollution Exposures apa itu diabetes blisters as Novel Insights into relationship of environmental inequalities and Association between longterm exposure to ambient air Ambient air pollution and diabetes A systematic review and Ambient air pollution exposure plasma metabolomic markers Purpose of Review Diabetes mellitus is a top contributor to the global burden of mortality and disability in adults There has also been a slow but steady rise in prediabetes and type 2 diabetes in youth The current review summarizes recent findings regarding the impact of increased exposure to air pollutants on the type 2 diabetes epidemic Recent Findings Human and animal studies provide Existing evidence indicates a positive association of air pollution and T2DM risk albeit there is high risk of bias Highquality studies assessing doseresponse effects are needed Research should be expanded to developing countries where outdoor and indoor air pollution are high Since most risk factors are uncontrollable air pollution acting as an intervening factor may provide a turning point for the prevention of diabetes and reduce the heavy burden caused by this To our knowledge there are no prior studies reporting this synergism between dietary habits and air pollution exposure on the risk of diabetes although a few studies have observed attenuated risk of negative health impacts of air pollution from intake of nutritional supplements with antiinflammatory properties for example omega3 Air Pollution Oxidative Stress and Diabetes a Life Course Type 2 DM and metabolic syndrome as a susceptibility factor for airpollution effects Diabetic patients have previously been shown to be more susceptible to air pollutioninduced cardiovascular morbidity and mortality 6 7 A few studies have examined the underlying mechanisms Ambient Air Pollution An Emerging Risk Factor for Diabetes Recent experimental and epidemiologic studies have suggested air pollution as a new risk factor for type 2 diabetes mellitus T2DM We conducted a systematic review of the epidemiologic studies on the association of air pollution with T2DM and related outcomes published by December 2013 We identified 22 studies six prospective studies on incident T2DM two prospective study on diabetes Air Pollution and Type 2 Diabetes Mechanistic Insights Emerging evidence indicates an association between longterm exposure to ambient air pollution AP and an increased risk of type 2 diabetes T2D 15 29 40 53 While the association has been established the underlying mechanisms through which AP increases the risk of T2D remain unclear The Global Burden of Diseases Injuries and Risk Factors Study 2017 GBD 2017 reported that air pollution AP was the eighth leading risk for death Globally a total of 294 million deaths 525 of all deaths were attributable to ambient particulate matter pollution GBD 2017 Ambient Air Pollution and Type 2 Diabetes Mellitus A Growing evidence supports that air pollution has become an important risk factor for developing diabetes mellitus Understanding the contributing effect of air pollution in population studies elucidating the potential mechanisms involved and identifying the most responsible pollutants are all required in order to promulgate successful changes in policy and to help formulate preventive Ambient air pollution associated with incidence and dynamic Association Between Environmental Air Pollution and Thyroid The last decade of air pollution epidemiology and the Ambient Air Pollution An Emerging Risk Factor for Diabetes Air Pollution Oxidative Stress and Diabetes a Life Course Association between air pollution and type 2 diabetes an Air pollution exposure and cardiometabolic risk The Lancet Air Pollution as a Risk Factor for Type 2 Diabetes PMC Recent studies in both humans and animals suggest that air pollution is an important risk factor for type 2 diabetes mellitus T2DM However the mechanism by which air pollution mediates propensity to diabetes is not fully understood While a Background Though the association between air pollution and incident type 2 diabetes T2D has been well documented evidence on the association with development of subsequent diabetes complications and postdiabetes mortality is scarce We investigate whether air pollution is associated with different progressions and outcomes of T2D Methods Based on the UK Biobank 398993 participants free Ambient obat bengkak kaki karena diabetes PM 25 ranked as the third leading risk factor for type 2 diabetes within the GBD hierarchy after high fasting plasma glucose and high bodymass index 17 Approximately a fifth of the global burden of type 2 diabetes was attributable to air pollution with 134 from ambient PM 25 and 65 from household air pollution Association between ambient air pollution and diabetes Background The global incidence of thyroid cancer has increased over the past several decades While this increase is partially due to increased detection environmental pollutants have also emerged as a possible contributing factor Our goal was to perform a systematic review to assess the relationship between environmental air pollution and thyroid cancer Methods Systematic literature Ambient Air Pollution An Emerging Risk Factor for Diabetes Ambient air pollution an emerging risk factor for diabetes Purpose of Review Ambient air pollution is strongly linked to cardiovascular and respiratory diseases We summarize available published evidence regarding similar associations with diabetes across the life course Recent Findings We performed a lifecourse survey of the recent literature including prenatal gestational childhoodadolescence and adult exposures to air pollution Oxidative Air pollution as a risk factor for type 2 diabetes PubMed Epidemiologic research and quantitative risk assessment play a crucial role in transferring fundamental scientific knowledge to policymakers so they can take action to reduce the burden of ambient air pollution This commentary addresses several challenges in quantitative risk assessment of air pollution that require close attention The background to this discussion provides a summary of and We reviewed 86 studies on air pollution and diabetes and its traits We metaanalyzed 29 studies for PM and NO2 with diabetes Air pollutants eg PM and NO2 are associated with higher odds of diabetes Air pollution is associated with dysregulation of glucose metabolism Estimates trends and drivers of the global burden of type 2 There is an emerging body of literature implicating ambient air pollution exposure as a potential risk factor for diabetes as demonstrated by several literature reviews and metaanalyses 4 5 Associations between longterm exposure to ambient air Background Substantial inequalities in the overall prevalence and patterns of multimorbidity have been widely reported but the causal mechanisms are complex and not well understood This study aimed to identify common patterns of multimorbidity in Serbia and assess their relationship with air pollutant concentrations and water quality indicators Methods This ecological study was conducted on The Global Burden of Disease assessment estimates that 20 of global type 2 diabetes cases are related to chronic exposure to particulate matter PM with a diameter of 25 μm or less PM25 With 99 of the global population residing in areas where air pollution levels are above current WHO air quality guidelines and increasing concern in regard to the common drivers of air pollution and Abstract Recent studies in both humans and animals suggest that air pollution is an important risk factor for type 2 diabetes mellitus T2DM However the mechanism by which air pollution mediates propensity to diabetes is not fully understood While a number of epidemiologic studies have shown a positive association between ambient air Reports from the Global Burden of Disease Injuries and Risk Factors Study 2017 indicated that air pollution was the eighth leading risk factor for death 2 A total of 294 million deaths have been attributed to ambient particulate matter pollution globally 2 Furthermore a large number of studies have found that air pollution has been linked Indeed a number of epidemiological studies have investigated the association between exposure to ambient air pollution and increased type 2 diabetes mellitus T2DM incidence prevalence morbidity and mortality Additional research has investigated whether people with diabetes are more susceptible to the effects of air pollutants Growing evidence supports that air pollution has become an important risk factor for developing diabetes mellitus Understanding the contributing effect of air pollution in population studies elucidating the potential mechanisms involved and identifying the most responsible pollutants are all required in order bahaya penyakit diabetes kering to promulgate successful changes
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