antioxidant properties of caffeic acid on diabetes rats - Modulatory effect of caffeic acid in obat metrix diabetes alleviating diabetes and CA treatment of diabetic mice revealed a protective effect on the liver and kidney hypoglycemic and hypolipidemic properties and high protection against atherogenic outcomes The obtained results suggest that CA is a safe and potent agent against diabetes that acts as an effective antioxidant in reducing serum glucose lipid profile and to diabetes Diabetes marked by hyperglycemia due to defects in insulin action or secretion is often complicated by oxidative stress and inflammation Natural products like caffeic acid CA a polyphenolic compound in plants and coffee have demonstrated antioxidant properties Similarly zinc oxide Caffeic acid CA is a polyphenolderived from hydroxycinnamic acid and possesses numerous physiological properties including antioxidant antiinflammatory antiatherosclerotic immunestimulatory cardioprotective antiproliferative and hepatoprotective activities CA acts as a regulatory compound affecting numerous biochemical pathways and The treatment of diabetic animals with caffeic acid started on the second day after induction of diabetes with at a dose of 50 mg kg 1 ip for 7 consecutive days Results are presented as the percentage of bodyweight change calculated by the formula described in Material and Methods n 9 for each treatment Statistically significant How caffeic acid and its derivatives combat diabetes and its Efficacy of Caffeic Acid on Diabetes and Its Complications in PubMed How caffeic acid and its derivatives combat diabetes and its complications A systematic review kidney heart and liver as well as physiologic properties such as plasma glucose and insulin levels in STZinduced DM protects brain against oxidative stress and inflammation induced by diabetes in rats Molecular and Cellular Biochemistry PDF Antioxidant and antidiabetic effects of caffeic acid in a rat Efficacy of Caffeic Acid on Diabetes and Its Complications in the Mouse Modulatory effect of menurunkan diabetes caffeic acid in alleviating diabetes and PDF Antidiabetic antioxidant and antiinflammatory effects of caffeic The ameliorative effect of zinc acetate with caffeic acid in the animal On the other hand caffeic acid has been shown to have antihyperglycaemic action in diabetic animals 17 32 In the present study both caffeic acid and zinc acetate significantly p 005 reduced diabetesinduced elevation of NFBG and FBG in rats after 4 weeks treatment Figs 1 a and 2 a However complexing zinc acetate with caffeic Core Tip Diabetes mellitus has emerged as one of the most common metabolic disorders worldwide which can lead to other complications such as retinopathy nephropathy neuropathy and foot ulcersFree radicalinduced oxidative stress is one of the primary causes of diabetes Caffeic acid CA is a natural polyphenol obtained from various fruits and vegetables Abstract Purpose To determine the antioxidant and antidiabetic potential of a natural flavonoid caffeic acid in a streptozotocininduced diabetic rat model Methods Experimental diabetes was induced in Wistar rats using streptozotocin injection Caffeic acid was administered orally on daily basis for 5 weeks Antioxidant and antidiabetic effects of caffeic acid in a rat model of Caffeic acid administration resulted in significant enhancement of serum insulin level and decrease in blood glucose level of diabetic rat models and point towards the potential applicability of caffeic acid in the management of diabetes mellitus Purpose To determine the antioxidant and antidiabetic potential of a natural flavonoid caffeic acid in a streptozotocininduced diabetic rat Caffeic acid was shown to have an antidiabetic effect in streptozotocininduced diabetic rat model The administration of caffeic acid 25 mgkg and 35 mgkg body weight for 5 weeks reduced PDF Antioxidant and antidiabetic effects of caffeic acid in diagnostic criteria for diabetes mellitus a rat model of
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