atorvastatin for diabetes melitus and chronic kidney disease - Chronic Kidney Disease and Type 2 artikel diabetes genetik Diabetes Arlington VA American Diabetes Association 2021 Jun doi 102337db2021113 Statin therapy should be initiated if the patient has a history of ASCVD or other risk factors 157 Review Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus Cardiovascular and Atorvastatin Has a DoseDependent Beneficial Effect on Kidney Function Abstract Background HMG CoA reductase inhibitors statins are known to prevent cardiovascular disease and improve lipid profiles However the effects of statins on renal outcomes including decline in estimated glomerular filtration rate eGFR and proteinuria in patients with chronic kidney disease CKD are controversial Atorvastatin Has a DoseDependent Beneficial Effect on Kidney Function Type 2 diabetes mellitus without CHD Atorvastatin 10 mg vs placebo 38 Baseline y 1 y 2 y 3 y 4 ASPEN 2410 Type 2 diabetes mellitus withwithout CHD Chronic kidney disease and the risks of death cardiovascular events and hospitalization N Engl J Med 200435112961305 Google Scholar 2 Mitch WE Walser M Buffington GA Chronic kidney disease CKD study which enrolled 9297 patients with vascular disease or diabetes mellitus 7 The subset of patients with mild renal dysfunction had nearly twice the risk of cardiovascular mortality and allcause mortality The role of statins in chronic kidney disease Am J Med Sci 2005 3306981 Crossref Scopus 24 Effects of Statins on Renal Function Mayo Clinic Proceedings Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis N Engl J Lowdose atorvastatin in severe chronic kidney disease patients a randomized controlled endpoint Atorvastatin in Patients with Type 2 Diabetes Mellitus Undergoing Keywords Highintensity statin therapy Chronic kidney disease Cardiovascular events aktivitas untuk penderita diabetes glomerular filtration rate and albuminuria are independent predictors of cardiovasular events and death in type 2 diabetes mellitus the Fenofibrate Intervention and Event Lowering in Diabetes FIELD Study Subgroup analyses of major statinintervention trials documented a cardiovascular benefit in patients with chronic kidney disease stages 1 2 and 3 according to the classification of the Statin initiation and risk of incident kidney disease in PubMed Effects of Statins on Renal Outcome in Chronic Kidney Disease Patients The Interplay Between Diabetes Cardiovascular Disease and Kidney Type 2 diabetes mellitus without CHD Atorvastatin 10 mg vs placebo 38 Baseline y 1 y 2 y 3 y 4 ASPEN 2410 Type 2 diabetes mellitus withwithout CHD In addition equations from the Chronic Kidney Disease Epidemiology Collaboration that are adjusted for ethnic group were used to determine the estimated GFR and eGFR slopes over time People with diabetes and chronic kidney disease CKD are at high risk for kidney failure atherosclerotic cardiovascular disease heart failure and prema For primary prevention of ASCVD the ADA recommends a moderateintensity statin for all adults with diabetes aged 4075 years those aged 2039 years with additional ASCVD risk Diabetes Management in Chronic Kidney Disease A Consensus Report by CholesterolLowering Treatment in Chronic Kidney Disease Nature Abstract Background The role of statin therapy in the development of kidney disease in patients with type 2 diabetes mellitus DM remains uncertain We aimed to determine the relationships between statin initiation and kidney outcomes in patients with type 2 DM Methods Through a newuser design we conducted a multicentre retrospective Highintensity statin therapy in patients beras khusus diabetes with chronic kidney disease
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