breast cancer subtypes diabetes type 2 - Diabetes mellitus and risk of breast seminar diabetes 2019 cancer a largescale Nature Association between diabetes and clinicopathological breast cancer subtypes Breast cancer patients with diabetes had a similar distribution of morphology tumor size and number of positive lymph nodes compared to those without diabetes also if stratified for menopausal status Premenopausal breast cancer patients with diabetes had more often PRnegative OR 24495CI107555 p Purpose Breast cancer and its treatments may increase the risk of type 2 diabetes T2D We conducted a systematic review and metaanalysis to investigate the association between breast cancer and the incidence of T2D overall and according to breast cancer treatments Based on the articles used from the database and keyword searches there is an association between diabetes and breast cancer Type 2 diabetes is a medical disease that affects more than 7 of adults in developed countries Diabetes and breast cancer subtypes Bronsveld HK Jensen V Vahl P et al PLoS One 2017120 doi 101371journal Type 2 Diabetes and Breast Cancer The Interplay between Impaired The causality between Type 2 diabetes and breast cancer a Results Genetically predicted Type 2 diabetes presented no statistically significant association with overall breast cancer or its subtypes Similarly genetically predicted overall breast cancer or its subtypes had no causal effect on Type 2 diabetes Sensitivity analyses yielded similar results Conclusion Our bidirectional Mendelian Diabetes and incidence of breast cancer and its molecular subtypes A Diabetes and Breast Cancer Subtypes PLOS ONE 1 Introduction Global breast cancer incidence has been increasing during the last three decades Female breast cancer has overtaken lung cancer as the most commonly diagnosed cancer with a total of 226 million cases in the year 2020 Despite the steadily decreasing mortality rate of breast cancer in highresource countries breast cancer mengobati luka diabetes remains as the leading cause of cancer deaths Diabetes as a Risk Factor for Breast Cancer PMC PubMed Central PMC Type 2 diabetes mellitus and breast cancer are complex chronic heterogeneous and multifactorial diseases with common risk factors including but not limited to diet obesity and age It further discusses the outcome of this association on breast cancer subtype specificity and relates this dynamic molecular crosstalk to explain the Diabetes mellitus DM has been proposed to be positively associated with breast cancer BCa risk due to shared risk factors metabolic dysfunction and the use of antidiabetic medications We conducted a systematic review and metaanalysis to evaluate the association between DM and BCa risk We se The prognostic outcome of type 2 diabetes mellitus and breast cancer Introduction Diabetes mellitus and breast cancer are chronic diseases with increasing incidence in many countries 12Recent estimates indicate that diabetes prevalence is 91 among women in Europe and lifetime risk for breast cancer is 97 Most patients with diabetes 90 have type 2 disease characterized by reduced insulin secretion and insulin resistance with diagnosis in Abstract Metabolic disorders especially type 2 diabetes and its associated complications represent a growing public health problem Epidemiological findings indicate a close relationship between diabetes and many types of cancer including breast cancer risk which regards not only the dysmetabolic condition but also its underlying risk factors and therapeutic interventions Table 2 Associations of diabetes its subtypes medications for type 2 diabetes and type 2 diabetes duration with breast cancer risk among 250312 female participants in the UK Biobank Full size Breast cancer and incidence of type 2 diabetes mellitus a PubMed Diabetes and Breast Cancer Subtypes PMC PubMed Central PMC Type 2 Diabetes Mellitus bila minum minyak zaitun dan obat diabetes and Clinicopathological Tumor Characteristics
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