aspilet clopidogrel ischemic stroke diabetes mellitus - Aspirin Versus Clopidogrel Monotherapy for the obat diabetes gluco Secondary Prevention Type 2 diabetes mellitus T2DM and stroke are two different diseases but have many aspects in common Aspirin is recommended as an initial treatment for the secondary prevention of recurrent ischemic stroke in patients with T2DM However clopidogrel In patients with minor ischemic stroke or highrisk TIA those who received a combination of clopidogrel and aspirin had a lower risk of major ischemic events but a higher risk of major hemorrhage at 90 days than those who received aspirin alone Funded by the National Institute of Neurological Diabetes mellitus patients are associated with improved clinical outcomes in highrisk patients diabetics patients treated with antiplatelet agents remain at higher risk of recurrent ischemic events Patients experiencing acute ischemic stroke or transient ischemic attack are commonly treated with clopidogrel andor aspirin mono and dualantiplatelet therapy to minimize the risk for recurrent stroke Updated data from systematic studies can be Efficacy and safety of clopidogrel andor aspirin for ischemic Introduction Type 2 diabetes mellitus T2DM and stroke are two different diseases but have many aspects in common Aspirin is recommended as an initial treatment for the secondary prevention of recurrent ischemic stroke in patients with T2DM However clopidogrel is an oral antiplatelet drug Combination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient ischemic attack TIA A trial of combination antiplatelet therapy in a Chinese population has shown a reduction in the Objectives Diabetes mellitus DM is a significant risk factor for ischemic stroke and associated with platelet reactivity We aim to evalua Clopidogrel highontreatment platelet reactivity in acute ischemic Clopidogrel monotherapy was neither inferior nor superior to aspirin monotherapy for the secondary prevention of recurrent cerebrovascular attack following previous ischemic stroke in patients with T2DM Hence clopidogrel or aspirin monotherapy is equally safe and effective in these patients Recurrent stroke is common immediately following a transient ischemic attack TIA or ischemic stroke Dual antiplatelet therapy DAPT with clopidogrel and aspirin may provide greater protection against subsequent stroke than monotherapy Electronic databases were searched for randomized clinical The PLATelet inhibition and patient that ticagrelor when compared to clopidogrel reduced ischemic events in ACS patients irrespective of diabetes status and glycemic control without an increase in major bleeding Combination Aspirin and Clopidogrel for Secondary Prevention abstrak diabetes of Ischemic cardiovascular disease and acute coronary syndromes ACS56 Studies have shown that patients with diabetes mellitus DM exhibit a poorer response to clopidogrel than patients without DM78 leading to a significant difference in the incidence of recurrence Clopidogrel and aspirin after ischemic stroke or transient ischemic Original Article from The New England Journal of Medicine Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack Diabetes mellitus is associated with an increased risk of stroke and poor outcome following a stroke event We assessed the impact of discharge treatm A literature review of antiplatelet agents for primary and secondary stroke prevention including mechanism of action cost and reasons for lack of benefitArticles were gathered from MEDLINE Cochrane Reviews and PubMed databases 19802021 Abstracts ClopidogrelHTPR was found in 44 of the patients with acute ischemic stroke Besides timedependency of the clopidogrel effect major risk factors for clopidogrelHTPR were diabetes mellitus and higher HbA1c values Further investigations are required to analyse if a function test guided strategy Keywords Stroke TIA Prevention Aspirin Clopidogrel Dipyridamole Small vessel disease Atrial fibrillation Cardioembolic Large vessel Stroke is the leading cause of adultacquired disability in most places in the world and the secondleading cause of death worldwide 24 In the era of contemporary secondary prevention strategies patients approximately one in seven patients will have a recurrent event within one year of their first stroke or TIA Transient Ischemic Attack 5 Background Despite increased atherothrombotic risk in type 2 diabetes mellitus T2DM the best preventative antithrombotic strategy remains undetermined We defined the effects of three antiplatelet agents on functional readout and biomarker kinetics in platelet activation and coagulation Clopidogrel and Aspirin in Acute Ischemic Stroke and HighRisk Clopidogrel and Aspirin in Acute Ischemic Stroke and HighRisk PDF Background and objective Diabetes mellitus is associated with an increased risk of stroke and poor outcome following a stroke event We assessed Find read and cite all the research you need on ResearchGate Antiplatelet Use in Ischemic Stroke PMC Current Antiplatelet Treatment Strategy in Patients with Diabetes Longterm effect of clopidogrel in patients with and without Combination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient ischemic attack TIA A trial of combination antiplatelet therapy in a Chinese population has shown dm tipe 3 a reduction in the
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